I've been very impressed with SaneBox - it certainly helps ease my general email anxiety by separating out the emails that have people I actually am in correspondence with from all other emails. I particularly like the features that allow me to drag and drop emails into action oriented folders (SaneLater or Archive) where I don't have to see them again! I also love that there is a digest so I can pick out the emails that may accidentally have gotten sorted as unimportant (usually from new contacts who I've never emailed before). For me, more so than time, it saves me the hassle of having to visually deal with clutter in my inbox. For any organizing junkies out there, I would highly recommend SaneBox.